Effects of antiarrhythmic drugs on defibrillation.
نویسندگان
چکیده
منابع مشابه
The effect of newer antiarrhythmic drugs on defibrillation threshold.
This study was conducted to determine the effects of clofilium phosphate and bretylium tosylate on ventricular defibrillation threshold. Dogs were anesthetized with pentobarbital and subjected to repeated fibrillation-defibrillation episodes. Defibrillation thresholds were determined at 15-min intervals, using underdamped 5--6 msec sinusoidal current shocks, from 30 min before drug injection to...
متن کاملElevation of ventricular defibrillation threshold in dogs by antiarrhythmic drugs.
Effects of antiarrhythmic drugs upon the threshold delivered energy (TDE) and threshold peak current (TPC) for electrical ventricular defibrillation by damped sinusoidal shocks were investigated in 25 pentobarbital-anesthetized dogs. TDE and TPC were increased by the three antiarrhytmic drugs tested. Bolus injections produced a transient rise and continuous infusions produced a steady rise in d...
متن کاملAlteration of defibrillation threshold by antiarrhythmic drugs: a theoretical framework.
Alteration of defibrillation threshold by antiarrhythmic drugs: a theoretical framework" (1981). Weldon School of Biomedical Engineering Faculty Publications. Paper 84.
متن کاملAntiarrhythmic drugs.
Most patients with cardiac arrhythmias require treatment with antiarrhythmic drugs, although recent advances in surgical and electrical techniques are promising. The ideal antiarrhythmic compound should have: (1) A wide range of therapeutic activity in both atrial and ventricular arrhythmias. (2) Parenteral and oral formulations to permit simple dosage schedules. (3) Pharmacokinetic properties ...
متن کاملAntiarrhythmic Drugs
Cardiac arrhythmias result from alterations in the orderly sequence of depolarization followed by repolarization in the heart. Cardiac arrhythmias may result in alterations in heart rate or rhythm and arise from alterations in impulse generation or conduction. The clinical implications of disordered cardiac activation range from asymptomatic palpitations to lethal arrhythmia. Pharmacological ma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Electrocardiology
سال: 1993
ISSN: 1884-2437,0285-1660
DOI: 10.5105/jse.13.10